| ORIGINAL ARTICLE |
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| Year : 2023 | Volume
: 9
| Issue : 1 | Page : 1-6 |
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Effect of acute exercise on Cardiovascular and Serum cortisol reactivity to mental stress in offspring of hypertensives
Pooja Sardar Nigade1, VP Varshney1, Mona Bedi2
1 Department of Biochemistry, Maulana Azad Medical College, And associated hospitals, New Delhi, India
2 Department of Physiology, Maulana Azad Medical College, New Delhi, India
Correspondence Address:
MBBS, MD, DNB Physiology Pooja Sardar Nigade
Senior resident, Department of Physiology, Maulana Azad Medical College, And associated hospitals. New Delhi – 110002
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/mamcjms.mamcjms_2_23
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Introduction: The purpose of our study was to evaluate the effect of acute exercise on HR, BP and serum cortisol levels in offspring of hypertensives. This could serve as a preventive measure to habituate the high risk population group right at the early age. Material and Methods: The study was a double blind single centered randomized controlled prospective study conducted in the Department of Physiology & Biochemistry, Maulana Azad Medical College and associated hospitals, New Delhi over a period of 1 year. 30 subjects were recruited for the study. They were labelled as:- Group 1–the subjects were rested for 10 minutes after which the measurement of BP, HR and Serum cortisol was done. This resting value was labeled as R-1. The subjects were then exposed to mental arithmetic test (MAT) for 5 minutes. Thereafter their BP, HR and Serum Cortisol were measured again and labeled as T-1. Group 2–Same subjects were similarly rested for 10 minutes after which the measurement of BP, HR and S. cortisol was done. This resting value was labeled as R-2. This was followed by 20 minutes of Bicycle ergometry exercise. The subjects were then exposed to MAT for 5 minutes. Thereafter their BP, HR and Serum cortisol were measured again and labeled as T-2. We then compared (T2–R2) known as Cardio-Adrenal Reactivity (CAR) with exercise vs CAR without exercise (T1-R1). 2ml of blood sample was withdrawn for estimation S. cortisol. Paired t-test was applied for comparison (p value <0.05–significant). Results: The CAR was more in Group 1 compared to Group 2, difference being statistically significant. Conclusion: Study showed statistically significant change between with and without exercise groups. Acute exercise can reduce the adrenocortical reactivity to stress, a preventive tool for development of future hypertension.
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