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Year : 2021  |  Volume : 7  |  Issue : 3  |  Page : 239-243

Prevalence and Etiology of Thrombocytopenia in Pregnant Women in a Tertiary Care Hospital in Delhi

1 Department of Pathology, Maulana Azad Medical College, New Delhi, India
2 Lady Hardinge Medical College, New Delhi, India

Correspondence Address:
Sarika Singh
Department of Pathology, Maulana Azad Medical College, New Delhi-110002
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mamcjms.mamcjms_52_21

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Background: Thrombocytopenia is the second most common hematologic abnormalities in pregnancy next to anemia. Its etiology is not well understood in the pregnant females. Aim: To find out the prevalence of thrombocytopenia (hospital based) in pregnant women and the various etiologic factors responsible for thrombocytopenia in pregnant Indian women. Setting and Design: This was a prospective, cross-sectional study. Materials and Methods: One thousand pregnant registered females attending the antenatal clinic were studied with detailed history, examination, hemogram on Sysmex KX-21 hematology analyzer (Transasia: Mumbai, India Diamed, Switzerland) five part differential analyzer in blood collected in ethylenediaminetetraacetic acid vials, liver and kidney function tests, and other relevant special hematologic tests depending upon the clinical diagnosis. Statistical Analysis: By using the Chi-squared test, values of P < 0.05 being considered statistically significant. Results: The prevalence of thrombocytopenia in pregnancy was 134/1000 (13.4%). Moderate thrombocytopenia was observed in 72/134 (53.7%) and severe thrombocytopenia in 14/134 (10.4%). About 125/134 (93.3%) of the thrombocytopenic patients were in the third trimester. Majority of them belonged to 21 to 25 years of age and had B+ blood group. Most common etiology was gestational thrombocytopenia (GT) in 46/134 (34.3%). Anemia was found in 27/134 (20.1%) patients. Conclusion: In Indian thrombocytopenic female, most common cause is GT but lesser than western world. The prevalence of associated anemia is higher in this part of world.

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