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REVIEW ARTICLE
Year : 2021  |  Volume : 7  |  Issue : 3  |  Page : 181-186

COVID-19 and Blood Disorders


1 Room Number 330, LNRDH Maulana Azad Medical College, New Delhi, India
2 BL Taneja Block, Department of Medicine, MAMC and LNH, New Delhi, India
3 B22 Hudco Place Extension, New Delhi, India

Correspondence Address:
Dr. Sunita Aggarwal
Department of Medicine, MAMC and LNH, B L Taneja Block, New Delhi-110002
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mamcjms.mamcjms_83_21

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In December 2019, a new type of coronavirus, severe acute respiratory syndrome coronavirus 2 was detected in Wuhan, Hubei province, China. It is currently a pandemic, with more than 185 million cases and roughly 4 million deaths globally as of July 9, 2021, with the United States and India leading the way. Coronavirus disease 2019 (COVID-19) may show multisystem involvement with significant impact on hematopoietic system and hemostasis. Blood count abnormalities, that is, lymphopenia (83.2%) and neutrophilia (34.5%), are of prognostic significance. Changes in hemostatic biomarkers represented by increase in D-dimer (23.3%) and associated thrombocytopenia (36.3%) indicate the essence of coagulopathy reported in these patients leading to fatal implications such as disseminated intravascular coagulation and serious thrombotic complications. Hence, accurate evaluation of laboratory indicators at the beginning and during COVID-19 can help health professionals in adjusting appropriate treatment and providing special and prompt care for those who need it. This study aims to highlight these abnormalities and appropriate interventions aimed to reduce the associated mortality of the disease. The effect of COVID-19 in patients with hematologic abnormalities and role of vaccination are also outlined.


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