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Year : 2021  |  Volume : 7  |  Issue : 2  |  Page : 165-167

Kikuchi Disease: Masquerading as Tubercular Cervical Lymphadenopathy

1 Department of Respiratory Medicine, School of Medical Sciences & Research, Gautam Budh Nagar, Uttar Pradesh, India
2 Pathology Consultancy Services, Noida, Uttar Pradesh, India

Correspondence Address:
Dr. Devendra Kumar Singh
Department of Respiratory Medicine, School of Medical Sciences & Research, 52 Karma Cottage, Allipur, Mandola, Ghaziabad, Uttar Pradesh 201102
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mamcjms.mamcjms_126_20

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Kikuchi–Fujimoto disease, also known as “histiocytic necrotizing lymphadenitis,” is a rare, benign disease that commonly affects young females. Patient usually presents with swollen lymph nodes in neck (cervical lymphadenopathy), fever, night sweats, weight loss, nausea, and vomiting. Due to the similar symptomatology, the disease is often confused with tuberculosis and lymphomas. The exact cause remains unknown with no evidence of inheritance. The diagnosis is confirmed by histopathologic examination of lymph node biopsy, which reveals necrosis (that varies considerably from one case to another), histiocytes (contains phagocytosed debris), crescentic nuclei, karyorrhexis, and plasmacytoid monocytes. The disease is self-remitting within 1 to 4 months. However, nonsteroidal anti-inflammatory drugs (NSAIDs), oral corticosteroids, and hydroxychloroquine may be used for symptomatic relief.

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